Modern Nano- and Bioelectroanalysis

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Team leader: prof. dr hab. Anna M. Nowicka

Team leader’s e-mail address: anowicka@chem.uw.edu.pl

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Brief description of the research topic:

The scientific activities of the Modern nano- and bioelectroanalysis group concern on bioengineering and surface imaging, the design of diagnostic tools, the search for new biomarkers of disease, and selective receptors for their determination. We focuse our attention on the various types of surface nanomodifiers that allow us control the packing density, orientation and organization of immobilized molecules (receptors). We design nanomaterials with given properties that allow selective and unambiguous determination of levels of biomarkers or gene mutations in body fluids and tissue extracts, as well as other simple analytes (e.g., metal cations, antibiotics) in environmental samples. The biomarker sensors we are developing are diagnostic tools, allowing us not only to confirm a disease, but also to correlate biomarker levels with disease stage. In addition to advanced analytics, we also conduct research focused on modern drug delivery systems (targeted therapy), including carrier design, drug loading or determining the release profile and how the drug enters the cell. In designing modern drug delivery systems, we aim to minimize the effect of drug resistance and side effects of anti-cancer therapies, as well as increase the efficiency of drug delivery to the diseased site. Our group’s research is perfectly in line with the trends of modern analytics and medicine regarding both personalized cancer therapy based on patients’ biological material (exosomes), diagnostic procedures (liquid biopsy) and environmental pollution.